Joint Universal Modular Plasmids (JUMP): A flexible and comprehensive platform for synthetic biologyValenzuela-Ortega, M. & French, C.E. (2019).

Joint Universal Modular Plasmids (JUMP): A flexible and comprehensive platform for synthetic biology.

Millacura, F.A., Li, M., Valenzuela-Ortega, M., & French C.E. (2019). TOBIAS: Transcription-Only Biological Information Algorithmic Systems as a novel cell-free approach for Synthetic Biology. In preparation

Millacura, F. A., Largey, B., & French, C. E. (2019). ParAlleL: a novel population-based approach to biological logic gates. Frontiers in Bioengineering and Biotechnology7.

Fig. 2

Wan, X., Volpetti, F., Petrova, E., French, C., Maerkl, S. J., & Wang, B. (2019). Cascaded amplifying circuits enable ultrasensitive cellular sensors for toxic metals. Nature chemical biology, 1.

Fig. 6Liu, W., Liu, W., Luo, Z., Wang, Y., Pham, N.T., Tuck, L., Pérez-Pi, I., Liu, L., Shen, Y., French, C., Auer, M. and Marles-Wright, J. (2018). Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods. Nature communications9(1), 1936.

Fig. 1

Kane, S. D., & French, C. E. (2018). Characterisation of novel biomass degradation enzymes from the genome of Cellulomonas fimiEnzyme and microbial technology113, 9-17.

Salinas, A., & French, C. E. (2017). The enzymatic ulvan depolymerisation system from the alga-associated marine flavobacterium Formosa agariphila. Algal Research27, 335-344.

Duedu, K. O., & French, C. E. (2017). Two-colour fluorescence fluorimetric analysis for direct quantification of bacteria and its application in monitoring bacterial growth in cellulose degradation systems. Journal of Microbiological Methods135, 85-92.

Duedu, K. O., & French, C. E. (2017). Data for discriminating dead/live bacteria in homogenous cell suspensions and the effect of insoluble substrates on turbidimetric measurements. Data in Brief12, 169-174.

publication-chris-french-lab-1-240x280Shen, Y., Wang, Y., Chen, T., Gao, F., Gong, J., Abramczyk, D., & 33 others including French, C. E., … & Luo, Y. (2017). Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome. Science355(6329), eaaf4791.

publication-chris-french-lab-3-240x280Duedu, K. O., & French, C. E. (2017). Two-colour fluorescence fluorimetric analysis for direct quantification of bacteria and its application in monitoring bacterial growth in cellulose degradation systems. Journal of Microbiological Methods135, 85-92.

publication-chris-french-lab-2-240x280Trubitsyna, M., Michlewski, G., Finnegan, D. J., Elfick, A., Rosser, S. J., Richardson, J. M., & French, C. E. (2017). Use of mariner transposases for one-step delivery and integration of DNA in prokaryotes and eukaryotes by transfection. Nucleic Acids Research, 1.

publication-chris-french-lab-5-240x280Duedu, K. O., & French, C. E. (2016). Characterization of a Cellulomonas fimi exoglucanase/xylanase-endoglucanase gene fusion which improves microbial degradation of cellulosic biomass. Enzyme and Microbial Technology, 93, 113-121.


Trubitsyna, M.Liu, C. K.Salinas, A., Elfick, A., & French, C. E. (2016). PaperClip: A Simple Method for Flexible Multi-Part DNA Assembly. Synthetic DNA: Methods and Protocols, 111-128.


Lakhundi, S. S., Duedu, K. O., Cain, N., Nagy, R., Krakowiak, J., & French, C. E. (2016). Citrobacter freundii as a test platform for recombinant cellulose degradation systems. Letters in applied microbiology64(1), 35-42.


Fletcher, E., Pilizota, T., Davies, P. R., McVey, A., & French, C. E. (2016). Characterization of the effects of n-butanol on the cell envelope of E. coliApplied microbiology and biotechnology100(22), 9653-9659.

Trubitsyna, M., Chan, K., Cai, Y., Elfick, A., & French, C. (2015). BBF RFC 104: BrickClip–rapid assembly of multiple RFC10 BioBricks.


Joshi, N., Ngwenya, B. T., Butler, I. B., & French, C. E. (2015). Use of bioreporters and deletion mutants reveals ionic silver and ROS to be equally important in silver nanotoxicity. Journal of hazardous materials287, 51-58.


French, C. E., Horsfall, L., Barnard, D. K., Duedu, K. O., Fletcher, E., Joshi, N., … & Radford, D. (2015). Beyond genetic engineering: Technical capabilities in the application fields of biocatalysis and biosensors. In Synthetic Biology (pp. 113-137). Springer International Publishing.


Trubitsyna, M., Michlewski, G., Cai, Y., Elfick, A., & French, C. E. (2014). PaperClip: rapid multi-part DNA assembly from existing libraries. Nucleic acids research, gku829.


Lewicka, A. J., Lyczakowski, J. J., Blackhurst, G., Pashkuleva, C.,  …, Horsfall, L., Elfick, A., & French, C. E. (2014). Fusion of pyruvate decarboxylase and alcohol dehydrogenase increases ethanol production in Escherichia coliACS Synth. Biol., 3 (12), 976–978.


French, C. E., Barnard, D. K., Fletcher, E., Kane, S. D., Lakhundi, S. S., Liu, C. K., & Elfick, A. (2013). Chapter 6. Synthetic biology for biomass conversion. New and future developments in catalysis. Elsevier, Amsterdam, 115-140., 115-140.


Joshi, N., Ngwenya, B. T., & French, C. E. (2012). Enhanced resistance to nanoparticle toxicity is conferred by overproduction of extracellular polymeric substances. Journal of hazardous materials, 241, 363-370.


Mena-Benitez, G. L., Gandia-Herrero, F., Graham, S., Larson, T. R., McQueen-Mason, De Mora, K., Joshi, N., Balint, B. L., Ward, F. B., Elfick, A., & French, C. E. (2011). A pH-based biosensor for detection of arsenic in drinking water. Analytical and bioanalytical chemistry, 400(4), 1031-1039.


French, C. E., de Mora, K., Joshi, N., Elfick, A., Haseloff, J., & Ajioka, J. (2011, December). Synthetic biology and the art of biosensor design. The science and applications of synthetic and systems biology: Workshop summary (pp. 178-201). Washington DC: National Academies Press.


Schwarz-Linek, J., Dorken, G., Winkler, A., Wilson, L. G., Pham, N. T., French, C. E., … & Poon, W. C. K. (2010). Polymer-induced phase separation in suspensions of bacteria. EPL (Europhysics Letters), 89(6), 68003.


Tota‐Maharaj, K., Scholz, M., Ahmed, T., French, C. E., & Pagaling, E. (2010). The synergy of permeable pavements and geothermal heat pumps for stormwater treatment and reuse. Environmental technology, 31(14), 1517-1531.


Joshi, N., Wang, X., Montgomery, L., Elfick, A., & French, C. E. (2009). Novel approaches to biosensors for detection of arsenic in drinking water. Desalination, 248(1-3), 517-523.

publication-chris-french-lab-19-240x280French, C. E. (2009). Synthetic biology and biomass conversion: a match made in heaven?. Journal of the Royal Society Interface, rsif20080527.



Mena-Benitez, G. L., Gandia-Herrero, F., Graham, S., Larson, T. R., McQueen-Mason, S. J., French, C. E., … & Bruce, N. C. (2008). Engineering a catabolic pathway in plants for the degradation of 1, 2-dichloroethane. Plant physiology, 147(3), 1192-1198.



French, C. E., Bell, J. M., & Ward, F. B. (2008). Diversity and distribution of hemerythrin-like proteins in prokaryotes. FEMS microbiology letters, 279(2), 131-145.


Aleksic, J., Bizzari, F., Cai, Y., Davidson, B., De Mora, K., Ivakhno, S., … & French, C. E. (2007). Development of a novel biosensor for the detection of arsenic in drinking water. IET Synthetic biology, 1(1), 87-90.

French, C.E., Nicholson, J., Bizzari, F., Aleksic, J., Cai, Y., Seshasayee, S. L., ... & Ma, H. (2007). Arsenic biosensor: a step further. BMC Systems Biology1(1), S11.

Hannink, N. K., Rosser, S. J., French, C. E., & Bruce, N. C. (2003). Uptake and metabolism of TNT and GTN by plants expressing bacterial pentaerythritol tetranitrate reductase. Water, Air, & Soil Pollution: Focus3(3), 251-258.

Rosser, S. J., French, C.E., & Bruce, N. C. (2001). Engineering plants for the phytodetoxification of explosives. In Vitro Cellular & Developmental Biology-Plant37(3), 330-333.

publication-chris-french-lab-23-240x280Hannink, N., Rosser, S. J., French, C. E., Basran, A., Murray, J. A., Nicklin, S., & Bruce, N. C. (2001). Phytodetoxification of TNT by transgenic plants expressing a bacterial nitroreductase. Nature biotechnology, 19(12), 1168-1172.

Rosser, S. J., Basran, A., Travis, E. R., French, C.E., & Bruce, N. C. (2001). Microbial transformations of explosives. Advances in applied microbiology49, 1-35.

Walker, E.H., French, C.E., Rathbone, D.A., & Bruce, N.C. (2000). Mechanistic studies of morphine dehydrogenase and stabilization against covalent inactivation. Biochemical Journal345(3), 687-692.

Boonstra, B., Björklund, L., French, C.E., Wainwright, I., & Bruce, N. C. (2000). Cloning of the sth gene from Azotobacter vinelandii and construction of chimeric soluble pyridine nucleotide transhydrogenases. FEMS microbiology letters191(1), 87-93.

Boonstra, B., Rathbone, D. A., French, C.E., Walker, E. H., & Bruce, N. C. (2000). Cofactor regeneration by a soluble pyridine nucleotide transhydrogenase for biological production of hydromorphone. Applied and environmental microbiology66(12), 5161-5166.

publication-chris-french-lab-24-240x280French, C. E., Rosser, S. J., Davies, G. J., Nicklin, S., & Bruce, N. C. (1999). Biodegradation of explosives by transgenic plants expressing pentaerythritol tetranitrate reductase. Nature biotechnology, 17(5), 491-494.

Boonstra, B., French, C. E., Wainwright, I., & Bruce, N. C. (1999). The udhA gene of Escherichia coli encodes a soluble pyridine nucleotide transhydrogenase. Journal of bacteriology181(3), 1030-1034.

French, C. E., Binks, P. R., Rathbone, D. A., Rosser, S. J., Williams, R. E., Nicklin, S., & Bruce, N. C. (1999). The Degradation of Nitrate Ester Explosives and TNT by Enterobacter cloacae PB2. Novel Approaches for Bioremediation of Organic Pollution (pp. 59-69). Springer US.

Moody, P. C., Shikotra, N., French, C.E., Bruce, N. C., & Scrutton, N. S. (1998). Crystallization and preliminary diffraction studies of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2. Acta Crystallographica Section D: Biological Crystallography54(4), 675-677.


French, C. E., Nicklin, S., & Bruce, N. C. (1998). Aerobic degradation of 2, 4, 6-trinitrotoluene by Enterobacter cloacae PB2 and by pentaerythritol tetranitrate reductase. Applied and Environmental Microbiology, 64(8), 2864-2868.


(See Chris French Lab protocols)